Steven K Libutti Selected Research

Multiple Endocrine Neoplasia Type 1

1/2019	Tissue-specific induced DNA methyltransferase 1 (Dnmt1) in endocrine pancreas by RCAS-TVA-based somatic gene transfer system promotes β-cell proliferation.
11/2015	In vivo proton MR spectroscopy of pancreatic neuroendocrine tumors in a multiple endocrine neoplasia type 1 conditional knockout mouse model.
11/2014	Menin immunoreactivity in secretory granules of human pancreatic islet cells.
12/2012	Pasireotide (SOM230) is effective for the treatment of pancreatic neuroendocrine tumors (PNETs) in a multiple endocrine neoplasia type 1 (MEN1) conditional knockout mouse model.
6/2012	Sleeping parathyroid tumor: rapid hyperfunction after removal of the dominant tumor.
10/2009	Insulinoma.
12/2003	Results of initial operation for hyperparathyroidism in patients with multiple endocrine neoplasia type 1.

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Steven K Libutti Research Topics

Disease

97	Neoplasms (Cancer) 06/2022 - 01/2002
16	Neoplasm Metastasis (Metastasis) 01/2022 - 01/2002
16	Neuroendocrine Tumors (Neuroendocrine Tumor) 01/2021 - 04/2008
11	Insulinoma 10/2017 - 06/2002
10	COVID-19 01/2022 - 08/2020
9	Melanoma (Melanoma, Malignant) 02/2016 - 05/2002
8	Primitive Neuroectodermal Tumors (PNET) 01/2021 - 12/2011
7	Multiple Endocrine Neoplasia Type 1 01/2019 - 12/2003
6	Adenocarcinoma 01/2018 - 09/2002
6	Primary Hyperparathyroidism 09/2017 - 12/2002
5	Ovarian Neoplasms (Ovarian Cancer) 11/2016 - 06/2005
5	Hyperparathyroidism 09/2012 - 12/2002
4	Infections 01/2022 - 01/2009
4	Pancreatic Neoplasms (Pancreatic Cancer) 03/2017 - 01/2008
4	Mesothelioma 06/2013 - 12/2003
3	Hyperaldosteronism (Conn Syndrome) 01/2021 - 09/2010
3	Carcinogenesis 03/2016 - 01/2009
3	Multiple Endocrine Neoplasia (Multiple Endocrine Adenomatosis) 08/2013 - 06/2002
3	Gastrointestinal Neoplasms (Gastrointestinal Cancer) 03/2013 - 03/2012
3	Hypercalcemia (Milk Alkali Syndrome) 09/2012 - 11/2002
3	Thyroid Neoplasms (Thyroid Cancer) 12/2010 - 05/2002
3	Hypoglycemia (Reactive Hypoglycemia) 02/2010 - 06/2002
3	Colorectal Neoplasms (Colorectal Cancer) 07/2009 - 08/2002
3	Breast Neoplasms (Breast Cancer) 07/2009 - 01/2002
3	Carcinoma (Carcinomatosis) 09/2006 - 07/2002
2	Hyperplasia 11/2021 - 05/2006
2	Colonic Neoplasms (Colon Cancer) 11/2021 - 01/2008
2	Disease Progression 11/2021 - 01/2003
2	Weight Loss (Weight Reduction) 09/2021 - 02/2016
2	Circulating Neoplastic Cells 01/2021 - 02/2016
2	Hypertension (High Blood Pressure) 01/2021 - 09/2013
2	Endocrine Gland Neoplasms (Cancer, Endocrine) 11/2018 - 12/2010
2	Adenoma (Adenomas) 09/2013 - 09/2002
2	Rare Diseases (Rare Disease) 02/2013 - 07/2011

Drug/Important Bio-Agent (IBA)

25	Proteins (Proteins, Gene)FDA Link 01/2022 - 05/2002
11	Tumor Necrosis Factor-alpha (Tumor Necrosis Factor)IBA 11/2018 - 08/2002
10	Insulin (Novolin)FDA Link 01/2021 - 09/2002
7	Biological ProductsIBA 01/2022 - 02/2004
7	Messenger RNA (mRNA)IBA 01/2019 - 09/2002
7	Pharmaceutical PreparationsIBA 11/2018 - 05/2007
6	Peptides (Polypeptides)IBA 03/2021 - 02/2004
6	Angiogenesis InhibitorsIBA 09/2009 - 01/2003
5	Glucose (Dextrose)FDA LinkGeneric 06/2022 - 06/2002
5	Biomarkers (Surrogate Marker)IBA 01/2022 - 07/2009
5	RNA (Ribonucleic Acid)IBA 01/2021 - 12/2003
5	DNA (Deoxyribonucleic Acid)IBA 01/2021 - 12/2010
5	Hormones (Hormone)IBA 04/2020 - 02/2004
5	FilaminsIBA 12/2014 - 09/2008
5	Vascular Endothelial Growth Factor A (Vascular Endothelial Growth Factor)IBA 03/2009 - 09/2002
4	VaccinesIBA 08/2021 - 08/2020
4	1-(1-mercaptocyclohexaneacetic acid)-2-(O- methyl-L-tyrosine)-8-L-arginine- vasopressin (AAVP)IBA 03/2021 - 01/2009
4	GoldIBA 11/2018 - 01/2010
4	CytokinesIBA 10/2018 - 06/2005
4	Everolimus FDA Link 01/2018 - 03/2012
4	CalciumIBA 09/2012 - 12/2003
4	Melphalan (Alkeran)FDA LinkGeneric 07/2009 - 12/2003
3	LigandsIBA 03/2021 - 03/2016
3	dactolisibIBA 01/2018 - 01/2011
3	TOR Serine-Threonine KinasesIBA 01/2018 - 01/2011
3	CYT-6091IBA 01/2018 - 01/2010
3	CateninsIBA 11/2016 - 07/2014
3	Adrenocorticotropic Hormone (ACTH)FDA Link 06/2016 - 02/2004
3	Parathyroid Hormone (Parathormone)IBA 01/2016 - 12/2002
3	Cisplatin (Platino)FDA LinkGeneric 06/2013 - 12/2003
3	Sunitinib (Sutent)FDA Link 03/2012 - 01/2008
3	Complementary DNA (cDNA)IBA 02/2004 - 01/2002
3	EndostatinsIBA 10/2002 - 07/2002
2	Amino Acids FDA Link 06/2022 - 01/2021
2	KininsIBA 01/2022 - 09/2021
2	AngiotensinsIBA 01/2022 - 09/2021
2	ReninIBA 01/2022 - 09/2021
2	AerosolsIBA 01/2022 - 09/2021
2	Gemcitabine FDA Link 01/2022 - 09/2008
2	Mechanistic Target of Rapamycin Complex 1IBA 01/2021 - 01/2018
2	IntegrinsIBA 01/2020 - 01/2009
2	LuciferasesIBA 01/2018 - 11/2003
2	Paclitaxel (Taxol)FDA LinkGeneric 01/2018 - 12/2003
2	Phosphatidylinositol 3-Kinase (1 Phosphatidylinositol 3 Kinase)IBA 01/2018 - 02/2016
2	liposomal doxorubicin (Doxil)FDA Link 03/2016 - 02/2012
2	Octreotide (Sandostatin)FDA LinkGeneric 03/2016 - 03/2013
2	Indicators and Reagents (Reagents)IBA 07/2014 - 09/2008
2	A-Form DNA (A-DNA)IBA 01/2013 - 08/2011
2	Doxorubicin (Adriamycin)FDA LinkGeneric 03/2012 - 05/2007
2	Gold Colloid (Colloidal Gold)IBA 12/2010 - 01/2010
2	Hypoglycemic Agents (Hypoglycemics)IBA 10/2009 - 04/2008
2	MicroRNAs (MicroRNA)IBA 09/2009 - 07/2009

Therapy/Procedure

42	Therapeutics 11/2021 - 01/2002
12	Drug Therapy (Chemotherapy) 11/2016 - 01/2002
8	Parathyroidectomy 09/2017 - 11/2002
4	Radiofrequency Ablation 03/2016 - 11/2003
3	Aftercare (After-Treatment) 01/2022 - 12/2010
3	Thyroidectomy 08/2009 - 05/2002
3	Lasers (Laser) 01/2007 - 07/2002
2	Immunotherapy 01/2022 - 11/2021
2	Adrenalectomy 01/2021 - 09/2010
2	Pancreatectomy 01/2019 - 06/2002
2	Lymph Node Excision (Lymph Node Dissection) 01/2019 - 07/2003
2	Cytoreduction Surgical Procedures 06/2013 - 02/2013
2	Hyperthermic Intraperitoneal Chemotherapy 06/2013 - 02/2013
2	Injections 01/2010 - 09/2004